Bridging Clinical Care + Life Saving Health Research
Documents from Translational Research Centre for review or download. Please contact us if you have any questions.
TRC Information Pamphlet (PDF)
TRC Application Form (PDF)
Task Delegation Form (for CRIC Applications only)
Specimen Labelling (PDF)
Blood Sample Collection and Processing – PLASMA (PDF)
Blood Sample Collection and Processing – SERUM (PDF)
CSF Collection and Processing (PDF)
Bronchoalveolar Lavage Isolation and Processing (PDF)
Mononuclear Cell Isolation from Blood or Bone Marrow (PDF)
Shipment of Specimens (PDF)
DNA Isolation from Whole Blood (PDF)
Blood Collection and Processing for Isolation of RNA (PDF)
Saliva Collection and Processing using ORAgene Kits (PDF)
Fraser et al. (2019)
Anticytokine Therapies in Severe Coronavirus Disease 2019 Should Be Informed by Detailed Inflammatory Profiling and Specific Therapeutic Targets (PDF)
Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients (PDF)
Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients (PDF)
Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers (PDF)
Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation (PDF)
Fraser, D. et al. (2019)
Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients (PDF)
Loredana Marcovecchio, M et al. (2014)
Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): Urinary Screening and Baseline Biochemical and Cardiovascular Assessments. Diabetes Care; 37(3):805-813.. doi:10.2337/dc13-1634 (PDF)
Lawson, M et al. (2014)
The JDRF CCTN CGM TIME Trial: Timing of Initiation of continuous glucose Monitoring in Established pediatric type 1 diabetes: study protocol, recruitment and baseline characteristics. BMC Pediatrics; 14:183-191.. doi:10.1186/1471-2431-14-183 (PDF)
Knoppert, D. (2011)
The Worldwide Opioid Epidemic: Implications for Treatment and Research in Pregnancy and the Newborn. Pediatrics Drugs; 13(5):277-279. doi: 10.2165/11592700-000000000-00000 (PDF)
Kelly, L et al. (2014)
Oral Morphine Weaning for Neonatal Abstinence Syndrome at Home Compared with In-Hospital: An Observational Cohort Study. Pediatr Drugs; [Epub ahead of print]doi:10.1007/s40272-014-0096-y(PDF)
Bock, D et al. (2014)
The Health initiative Program for Kids (HIP kids): effects of a 1-year multidisciplinary lifestyle intervention on adiposity and quality of life in obese children and adolescents- a longitudinal pilot intervention study. BMC Pediatrics; 14(1):296-304.. doi:10.1186/s12887-014-0296-1 (PDF)
Radhakrishnan, D et al. (2014)
Translational Research in Pediatrics III: Bronchoalveolar Lavage. Pediatrics; 134(1):135-154. doi:10.1542/peds.2013-1911 (PDF)
Omatsu, T et al. (2014)
CXCL1/CXCL8 (GRO/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro. Am J Physiol Endocrinol Metab; 306:E1077–E1084, doi:10.1152/ajpendo.00659.2013 (PDF)
Gillio Meina, C et al. (2013)
Translational Research in Pediatrics II: Blood Collection, Processing, Shipping, and Storage. Pediatrics; 131(4):754-66. doi: 10.1542/peds.2012-1181 [Epub ahead of print]. (PDF)
Brisson, A. et al. (2012)
Translational Research in Pediatrics: Tissue Sampling and Biobanking. Pediatrics; 129:1-10. (PDF)
Yazdan-Ashoori, P. et al. (2011)
Elevated Plasma Matrix Metalloproteinases and their Tissue Inhibitors in Patients with Severe Sepsis. Journal of Critical Care; 26(6):556-65. doi:10.1016/j.jcrc.2011.01.008 (PDF)
Fraser, D. et al. (2011).
Severe Traumatic Brain Injury in Children Elevates Glial Fibrillary Acidic Protein in Cerebrospinal Fluid and Serum. Pediatr Crit Care Med; 12(3):319-324. (PDF)
Filler, G. et al. (2011).
Impaired GFR is the Most Important Determinant for FGF-23 Increase in Chronic Kidney Disease. Clinical Biochemistry; 44:435-437. (PDF)
De Souza YG and Greenspan JS. (2013)
Biobanking past, present and future: responsibilities and benefits. AIDS; 27(3):303-312. doi: 10.1097/QAD.0b013e32835c1244 (PDF)
Vaught, J et al. (2012)
Biospecimens and Biorepositories: From Afterthought to Science. Cancer Epidemiol Biomarkers Prev; 21:253-255 (PDF)
Baker, M. ( 2012) Biorepositories: Building better biobanks. Nature; 486(7401):141-6 (PDF)
Vaught, J. and Lockhart, NC. (2012)
The evolution of biobanking best practices. Clinica chimica acta; international journal of clinical chemistry; 413(19-20):1569-1575 (PDF)
ISBER (2012)
Best Practices for Repositories: Collection, Storage, Retrieval, and Distribution of Biological Materials for Research. Biopreservation and Biobanking; 10(2):79-161 (PDF)
Moore, HM. (2012)
The NCI Biospecimen Research Network. Biotechnic & histochemistry: official publication of the Biological Stain Commission; 87(1):18-23 (PDF)
NCI (2011)
National Cancer Institute. Best Practices for Biospecimen Resources (PDF)
Hallmans, G. and Vaught, JB. (2011)
Best Practices for Establishing a Biobank. Methods in Molecular Biology; 675:241-60. (PDF)
Vaught, J. (2011)
An NCI Perspective on Creating Sustainable Biospecimen Resources. Journal of the National Cancer Institute. Monographs; (42):1-7 (PDF)
Vaught, JB. et al. (2010)
International Efforts to Develop Biospecimen Best Practices. Cancer Epidemiology, Biomarkers & Prevention; 19:912-915 (PDF)
OECD (2010)
Guidelines on Human Biobanks and Genetic Research Databases. Eur J Health Law; 17(2):191-204. (PDF)
McGregor TL. et al. (2013)
Inclusion of Pediatrics Samples in an Opt-Out Biorepository Linking DNA to De-Identified Medical Records: Pediatric BioVU. Clin Pharmacol Ther; 93(2):204-211. doi: 10.1038/clpt.2012.230. [Epub 2012 Nov 21] (PDF)
Smith ME. and Aufox S. (2013).
Biobanking: The Melding of Research with Clinical Care. Curr Genet Med Rep: 1:122–128 (PDF)
Yassin R. et al (2012)
Sharing Individual Research Results with Biospecimen Contributors: Point. Cancer Epidemiol Biomarkers Prev: 2012;21:256-259 (PDF)
Dash, RC. et al. (2012)
Biospecimens and Biorepositories for the Community Pathologist. Archives of pathology & laboratory medicine; 136(6):668-678 (PDF)
The International Society of Biological and Environmental Repositories presents Abstracts from their Annual Meeting. Keeping Step in an Evolving Global Research Environment: Biobanking for Now and for the Future. Biopreservation and Biobanking; 10(2):181-231 (PDF)
Kay, AB. (2012)
Considerations for uniform and accurate biospecimen labelling in a biorepository and research environment. Journal in Clinical Pathology; 64(7):634-636 (PDF)
Tukacs, E. et al. (2012)
Model requirements for Biobank Software Systems. Bioinformation: 8(6):290-292 (PDF)
Grizzle, WE. et al. (2011)
What Are the Most Oppressing Legal and Ethical Issues Facing Biorepositories and What Are Some Strategies to Address Them?. Biopreservation and Biobanking; 9(4):317-319 (PDF)
Manley, GT. et al. (2010)
Common Data Elements for Traumatic Brain Injury: Recommendations From the Biospecimens and Biomarkers Working Group. Archives of Physical Medicine and Rehabilitation; 91(11):1667-1672 (PDF)
Bell, WC, et al. (2010)
Organizational Issues in Providing High-Quality Tissues and Clinical Information for the Support of Biomedical Research. Methods Mol Biol; vol. 576 (PDF)
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